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pentobarbital will minimize the extent or outcome of flurbiprofen by affecting hepatic enzyme CYP2C9/ten metabolism. Small/Significance Unknown.pentobarbital decreases amounts of panobinostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Robust CYP3A4 inducers can reduce panobinostat amounts by ~70% and cause procedur